PKA phosphorylates Myosin Binding Protein-C (MyBP-C) and troponin I (TnI) within the cardiac myofibril. TnI is definitely the inhibitory ingredient of your trimeric troponin molecule that makes up the Ca2+-swap of your contractile apparatus. TnI binds to TnC when Ca2+ is sure to TnC, although within the absence of Ca2+, the C-terminus of TnI is rel

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